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Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1) Peptide

ECH1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976109
  • Target See all ECH1 products
    ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ECH1 antibody (Catalog #: ARP43560_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
    Synonyms
    HPXEL Peptide, Pxel Peptide, AA617331 Peptide, enoyl-CoA hydratase 1, peroxisomal Peptide, enoyl CoA hydratase 1, peroxisomal Peptide, enoyl-CoA hydratase 1 Peptide, delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Peptide, enoyl-CoA hydratase 1, peroxisomal L homeolog Peptide, enoyl coenzyme A hydratase 1, peroxisomal Peptide, ech1 Peptide, ECH1 Peptide, LOC747511 Peptide, ech1.L Peptide, Ech1 Peptide
    Background
    ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The protein contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

    Alias Symbols: HPXEL

    Protein Interaction Partner: CSTF2,EEF1G,PAFAH1B3,SERPINB9,TIMP1,TLR10,CSTF2,EEF1G,PAFAH1B3,SERPINB9,TIMP1

    Protein Size: 328
    Molecular Weight
    36 kDa
    Gene ID
    1891
    NCBI Accession
    NM_001398, NP_001389
    UniProt
    Q13011
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