Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (C-Term) Peptide
FGF8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FGF8 products
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EGWYMAFTRK GRPRKGSKTR QHQREVHFMK RLPRGHHTTE QSLRFEFLNY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FGF8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) peptide (Ovalbumin)
FGF8 Reactivity: Human Host: Synthetic WB, Imm, SDS
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
- Synonyms
- Aigf Peptide, Fgf-8 Peptide, AIGF Peptide, FGF-8 Peptide, HBGF-8 Peptide, HH6 Peptide, KAL6 Peptide, fibroblast growth factor 8 Peptide, Fgf8 Peptide, FGF8 Peptide
- Background
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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
Alias Symbols: AIGF, HBGF-8, KAL6, MGC149376, FGF-8
Protein Interaction Partner: AR,FGFR1,FGFR2,FGFR3,FGFR4,FGFR3
Protein Size: 215 - Molecular Weight
- 22 kDa
- Gene ID
- 2253
- NCBI Accession
- NM_006119, NP_006110
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