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Forkhead Box O3 (FOXO3) Peptide

FOXO3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN977070
  • Target See all FOXO3 products
    FOXO3 (Forkhead Box O3 (FOXO3))
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-FOXO3 antibody (Catalog #: ARP38040_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FOXO3 (Forkhead Box O3 (FOXO3))
    Synonyms
    AF6q21 Peptide, FKHRL1 Peptide, FKHRL1P2 Peptide, FOXO2 Peptide, FOXO3A Peptide, zgc:92176 Peptide, wu:fb50g02 Peptide, wu:fi33f07 Peptide, Fkhrl1 Peptide, Foxo3a Peptide, FoxO3A Peptide, 1110048B16Rik Peptide, 2010203A17Rik Peptide, C76856 Peptide, Fkhr2 Peptide, FOXO-3 Peptide, FOXO3 Peptide, foxo3a Peptide, xfoxo3 Peptide, foxO3 Peptide, foxO Peptide, fkhr Peptide, foxo5 Peptide, wu:fj65a12 Peptide, zFkhr Peptide, forkhead box O3 Peptide, forkhead box O3A Peptide, forkhead box O3 L homeolog Peptide, forkhead box O3b Peptide, FOXO3 Peptide, foxo3a Peptide, Foxo3 Peptide, foxo3.L Peptide, foxo3 Peptide, foxO3 Peptide, foxo3b Peptide
    Background
    FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

    Alias Symbols: AF6q21, DKFZp781A0677, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, MGC12739, MGC31925

    Protein Interaction Partner: CDKN1A,CDKN1B,CHUK,FOXG1,IKBKB,SIRT1,SMAD3,SMAD4,BCL2L11,AKT1,CHUK,EP300,ESR1,FOXG1,IKBKB,NR1H2,NR1H3,SGK1,SIRT1,SMAD2,SMAD3,SMAD4,YWHAG,YWHAZ,CTNNB1,SMAD3,SMAD4,TP53,USP7,YWHAZ

    Protein Size: 673
    Molecular Weight
    71 kDa
    Gene ID
    2309
    NCBI Accession
    NM_001455, NP_001446
    UniProt
    O43524
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