General Transcription Factor IIA, 1-Like (GTF2A1L) Peptide
GTF2A1L
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GTF2A1L products
- GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GTF2A1L antibody (Catalog #: ARP50819_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))
- Synonyms
- ALF Peptide, 1700011N16Rik Peptide, Alf Peptide, Gtf2a1lf Peptide, general transcription factor IIA subunit 1 like Peptide, general transcription factor IIA, 1-like Peptide, general transcription factor 2A subunit 1 like Peptide, GTF2A1L Peptide, Gtf2a1l Peptide
- Background
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The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alias Symbols: ALF, MGC26254
Protein Interaction Partner: ASCL3,CSNK2A1,CSNK2A2,GTF2A2,ID3,SUB1,TBP
Protein Size: 478 - Molecular Weight
- 52 kDa
- Gene ID
- 11036
- NCBI Accession
- NM_006872, NP_006863
- UniProt
- Q9UNN4
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