General Transcription Factor IIE, Polypeptide 1, alpha 56kDa (GTF2E1) Peptide
GTF2E1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all GTF2E1 products
- GTF2E1 (General Transcription Factor IIE, Polypeptide 1, alpha 56kDa (GTF2E1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GTF2E1 antibody (Catalog #: P100892_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GTF2E1 (General Transcription Factor IIE, Polypeptide 1, alpha 56kDa (GTF2E1))
- Synonyms
- 2610024P03Rik Peptide, 56kDa Peptide, AI303800 Peptide, FE Peptide, TFIIE-A Peptide, DDBDRAFT_0168201 Peptide, DDBDRAFT_0168202 Peptide, DDBDRAFT_0231096 Peptide, DDB_0168201 Peptide, DDB_0168202 Peptide, DDB_0231096 Peptide, DDBDRAFT_0217176 Peptide, DDBDRAFT_0217177 Peptide, DDBDRAFT_0266401 Peptide, DDB_0217176 Peptide, DDB_0217177 Peptide, DDB_0266401 Peptide, TF2E1 Peptide, si:ch211-194d6.2 Peptide, gtf2e1 Peptide, tfiiealpha Peptide, general transcription factor II E, polypeptide 1 (alpha subunit) Peptide, general transcription factor IIE subunit 1 Peptide, transcription factor IIE Peptide, general transcription factor IIE subunit 2 Peptide, general transcription factor IIE, polypeptide 2, beta 34kDa Peptide, general transcription factor IIE, polypeptide 1, alpha Peptide, general transcription factor IIE subunit 1 L homeolog Peptide, Gtf2e1 Peptide, gtf2e1-1 Peptide, gtf2e1-2 Peptide, GTF2E2 Peptide, GTF2E1 Peptide, gtf2e1 Peptide, gtf2e1.L Peptide
- Background
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The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57,000 (TFIIE-alpha) and 34,000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation
Alias Symbols: FE, TF2E1, TFIIE-A
Protein Interaction Partner: AES,ERCC3,GTF2A1,GTF2A2,GTF2B,GTF2E2,GTF2F2,GTF2H1,GTF2H4,SND1,TAF6,TBP,TCEA1,TRIM24,AES,BRCA1,ERCC3,GTF2A1,GTF2B,GTF2E2,GTF2F1,GTF2F2,GTF2H4,MDM2,MED21,POLR2A,SND1,TAF1,TAF11,TAF6,TBP,TCEA1,TRIM24
Protein Size: 439 - Molecular Weight
- 49 kDa
- Gene ID
- 2960
- NCBI Accession
- NM_005513, NP_005504
- UniProt
- P29083
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