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5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) Peptide

HTR2A Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN978346
  • Target See all HTR2A products
    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
    Protein Region
    N-Term
    Origin
    Human, Mouse
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-HTR2A antibody (Catalog #: AVARP13044_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
    Synonyms
    5-HT2A Peptide, HTR2 Peptide, 5-HT-2 Peptide, 5-HT-2A Peptide, 5-HTR2A Peptide, LOC100009461 Peptide, E030013E04 Peptide, Htr-2 Peptide, Htr2 Peptide, 5Ht-2 Peptide, 5HT2A Peptide, 5HTR2A Peptide, HTR2A Peptide, Htr2a Peptide, 5HT2 Peptide, 5-hydroxytryptamine receptor 2A Peptide, 5-hydroxytryptamine (serotonin) receptor 2A Peptide, HTR2A Peptide, Htr2a Peptide
    Background
    HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.

    Alias Symbols: 5-HT2A, HTR2

    Protein Interaction Partner: ANKS1B,DLG4,EIF3F,GLUL,GNA11,GNAI1,GNAQ,JAK2,MAP1A,MRPL28,NDUFB10,NME3,NTRK3,PON2,PPP5C,RPS6KA3,DLG4,JAK2

    Protein Size: 471
    Molecular Weight
    52 kDa
    Gene ID
    3356
    NCBI Accession
    NM_000621, NP_000612
    UniProt
    P28223
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