Serotonin Receptor 3A (HTR3A) Peptide
HTR3A
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all Serotonin Receptor 3A (HTR3A) products
- Serotonin Receptor 3A (HTR3A)
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HTR3A antibody (Catalog #: AVARP13046_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Serotonin Receptor 3A (HTR3A)
- Synonyms
- MGC52789 Peptide, HTR3A Peptide, 5-HT3 Peptide, 5HT3R Peptide, HTR3 Peptide, 5-HT-3 Peptide, 5-HT3A Peptide, 5-HT3R Peptide, 5HT3 Peptide, Htr3 Peptide, 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic L homeolog Peptide, 5-hydroxytryptamine receptor 3A Peptide, 5-hydroxytryptamine (serotonin) receptor 3A Peptide, htr3a.L Peptide, HTR3A Peptide, Htr3a Peptide
- Background
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HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R
Protein Interaction Partner: CANX,HSPA5
Protein Size: 478 - Molecular Weight
- 55 kDa
- Gene ID
- 3359
- NCBI Accession
- NM_000869, NP_000860
- UniProt
- P46098
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