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Isopentenyl-Diphosphate delta Isomerase 1 (IDI1) Peptide

IDI1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978395
  • Target See all IDI1 products
    IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-IDI1 antibody (Catalog #: ARP54735_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))
    Synonyms
    zgc:114138 Peptide, 4832416K17Rik Peptide, ipp1 Peptide, ippl1 Peptide, IPP1 Peptide, IPPI1 Peptide, isopentenyl-diphosphate delta isomerase 1 Peptide, isopentenyl-diphosphate delta isomerase Peptide, isopentenyl-diphosphate delta isomerase 1 L homeolog Peptide, idi1 Peptide, Idi1 Peptide, idi1.L Peptide, IDI1 Peptide
    Background
    IDI1 is a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-492 BE891119.1 50-541 493-1758 BX648472.1 1201-2466 1759-2150 BX537663.1 4550-4941

    Alias Symbols: IPP1, IPPI1

    Protein Size: 284
    Molecular Weight
    32 kDa
    Gene ID
    3422
    NCBI Accession
    NM_004508, NP_004499
    UniProt
    Q13907
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