Isopentenyl-Diphosphate delta Isomerase 1 (IDI1) Peptide
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- Target See all IDI1 products
- IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IDI1 antibody (Catalog #: ARP54735_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))
- Synonyms
- zgc:114138 Peptide, 4832416K17Rik Peptide, ipp1 Peptide, ippl1 Peptide, IPP1 Peptide, IPPI1 Peptide, isopentenyl-diphosphate delta isomerase 1 Peptide, isopentenyl-diphosphate delta isomerase Peptide, isopentenyl-diphosphate delta isomerase 1 L homeolog Peptide, idi1 Peptide, Idi1 Peptide, idi1.L Peptide, IDI1 Peptide
- Background
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IDI1 is a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-492 BE891119.1 50-541 493-1758 BX648472.1 1201-2466 1759-2150 BX537663.1 4550-4941
Alias Symbols: IPP1, IPPI1
Protein Size: 284 - Molecular Weight
- 32 kDa
- Gene ID
- 3422
- NCBI Accession
- NM_004508, NP_004499
- UniProt
- Q13907
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