Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (N-Term) Peptide
IKBKE
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IKKi/IKKe (IKBKE) products
- IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AGAIAGAQRR ENGPLEWSYT LPITCQLSLG LQSQLVPILA NILEVEQAKC
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IKBKE Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
- Synonyms
- zgc:100844 Peptide, IKBKE Peptide, MGC130907 Peptide, IKK-E Peptide, IKK-i Peptide, IKKE Peptide, IKKI Peptide, AW558201 Peptide, IKKepsilon Peptide, Ikki Peptide, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon Peptide, inhibitor of nuclear factor kappa B kinase subunit epsilon Peptide, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog Peptide, inhibitor of kappaB kinase epsilon Peptide, IKBKE Peptide, ikbke Peptide, ikbke.L Peptide, Ikbke Peptide
- Background
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IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30 % of breast carcinomas and breast cancer cell lines.
Alias Symbols: IKK-i, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297, IKK-E
Protein Interaction Partner: TANK,AZI2,CDC37,FKBP5,HSP90AA1,HSP90AB1,IRF3,IRF5,KTN1,NFKBIA,SIKE1,TANK,TICAM1,ACLY,ATIC,CALCOCO2,CDC37,CLTC,CYLD,DSTYK,EPRS,FKBP5,HSP90AA2,HYOU1,IMPDH2,IRF3,KTN1,LARS,LRPPRC,MYH10,PABPC1,PDIA6,PLS3,PPP2R1A,PSMA7,RELA,ROCK2,RUVBL2,SND1,TANK,UBC,VCP
Protein Size: 631 - Molecular Weight
- 69 kDa
- Gene ID
- 9641
- NCBI Accession
- NM_001193321, NP_001180250
- UniProt
- Q3B754
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