Interleukin 17A (IL17A) (N-Term) Peptide
IL17A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Interleukin 17a (IL17A) products
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MTPGKTSLVS LLLLLSLEAI VKAGITIPRN PGCPNSEDKN FPRTVMVNLN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL17A Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
- Synonyms
- CTLA8 Peptide, IL-17 Peptide, IL-17A Peptide, IL17 Peptide, Ctla-8 Peptide, Ctla8 Peptide, Il17 Peptide, ChIL-17 Peptide, IL-17F Peptide, IL17A Peptide, CTLA-8 Peptide, interleukin 17A Peptide, IL17A Peptide, Il17a Peptide
- Background
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The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Alias Symbols: CTLA8, IL-17, IL-17A, IL17
Protein Interaction Partner: IL17A,IL17RA,IL17A
Protein Size: 155 - Molecular Weight
- 15 kDa
- Gene ID
- 3605
- NCBI Accession
- NM_002190, NP_002181
- UniProt
- Q16552
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