Jagged 2 (JAG2) Peptide
JAG2
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all JAG2 products
- JAG2 (Jagged 2 (JAG2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-JAG2 antibody (Catalog #: ARP45254_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- JAG2 (Jagged 2 (JAG2))
- Synonyms
- D12Ggc2e Peptide, Serh Peptide, mJagged2-1 Peptide, sm Peptide, HJ2 Peptide, SER2 Peptide, jag2 Peptide, serB Peptide, zgc:152855 Peptide, jagged 2 Peptide, jagged 2b Peptide, JAG2 Peptide, jag2 Peptide, Jag2 Peptide, jag2b Peptide
- Background
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The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch protein family are transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HJ2, SER2
Protein Interaction Partner: ATN1,GFI1B,NOTCH1,NOTCH2,NOTCH3,NOTCH1,NOTCH2,NOTCH3
Protein Size: 1238 - Molecular Weight
- 130 kDa
- Gene ID
- 3714
- NCBI Accession
- NM_002226, NP_002217
- UniProt
- Q9Y219
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