Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1) (Middle Region) Peptide
KCNB1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Kv2.1/KCNB1 (KCNB1) products
- Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KCNB1 antibody (Catalog #: ARP33975_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
- Synonyms
- KCNB1 Peptide, Kcnb1 Peptide, Kcr1-1 Peptide, Kv2.1 Peptide, Shab Peptide, DRK1PC Peptide, DRK1 Peptide, KV2.1 Peptide, h-DRK1 Peptide, potassium voltage-gated channel subfamily B member 1 Peptide, potassium voltage-gated channel, Shab-related subfamily, member 1 Peptide, potassium channel, voltage gated Shab related subfamily B, member 1 Peptide, potassium voltage gated channel, Shab-related subfamily, member 1 Peptide, KCNB1 Peptide, kcnb1 Peptide, LOC100541632 Peptide, Kcnb1 Peptide
- Background
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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DRK1, KV2.1, h-DRK1
Protein Interaction Partner: KCNB1,KCNG1,KCNG2,KCNG3,KCNG4,KCNS3,KCNV1,KCNV2,PTPRE,SNAP25,SRC,STX1A,KCNB1,KCNG2,KCNG3,KCNH1,KCNS3,KCNV2,PTPRE,SNAP25
Protein Size: 858 - Molecular Weight
- 96 kDa
- Gene ID
- 3745
- NCBI Accession
- NM_004975, NP_004966
- UniProt
- Q14721
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