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Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4) (Middle Region) Peptide

KCNC4 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN978758
  • Target See all Kv3.4 (KCNC4) products
    Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-KCNC4 antibody (Catalog #: ARP35161_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))
    Synonyms
    C1orf30 Peptide, HKSHIIIC Peptide, KSHIIIC Peptide, KV3.4 Peptide, AI850292 Peptide, Kcr2-4 Peptide, Kv3.4 Peptide, potassium voltage-gated channel subfamily C member 4 Peptide, potassium channel, voltage gated Shaw related subfamily C, member 4 Peptide, potassium voltage gated channel, Shaw-related subfamily, member 4 Peptide, KCNC4 Peptide, kcnc4 Peptide, Kcnc4 Peptide
    Background
    KCNC4 is part of the Shaker gene family of Drosophila. It encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. KCNC4 belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: HKSHIIIC, KSHIIIC, KV3.4, MGC126818, C1orf30

    Protein Size: 582
    Molecular Weight
    64 kDa
    Gene ID
    3749
    NCBI Accession
    NM_153763, NP_720198
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