Macrophage erythroblast Attacher (MAEA) (N-Term) Peptide
MAEA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MAEA products
- MAEA (Macrophage erythroblast Attacher (MAEA))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RFRAAQKNID RETSHVTMVV AELEKTLSGC PAVDSVVSLL DGVVEKLSVL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAEA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAEA (Macrophage erythroblast Attacher (MAEA))
- Synonyms
- emp Peptide, emlp Peptide, pig5 Peptide, hlc-10 Peptide, MGC81431 Peptide, MAEA Peptide, MGC64455 Peptide, MGC89777 Peptide, EMLP Peptide, EMP Peptide, GID9 Peptide, HLC-10 Peptide, PIG5 Peptide, 1110030D19Rik Peptide, Gid9 Peptide, wu:fb20a09 Peptide, zgc:63708 Peptide, macrophage erythroblast attacher S homeolog Peptide, macrophage erythroblast attacher Peptide, macrophage erythroblast attacher L homeolog Peptide, maea.S Peptide, MAEA Peptide, maea Peptide, Maea Peptide, maea.L Peptide
- Background
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This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes, this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Alias Symbols: EMLP, EMP, HLC-10, PIG5
Protein Interaction Partner: MYOC,UBC
Protein Size: 355 - Molecular Weight
- 40 kDa
- Gene ID
- 10296
- NCBI Accession
- NM_005882, NP_005873
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