Mediator Complex Subunit 26 (MED26) (N-Term) Peptide
MED26
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MED26 products
- MED26 (Mediator Complex Subunit 26 (MED26))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MED26 antibody (Catalog #: ARP33745_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MED26 (Mediator Complex Subunit 26 (MED26))
- Synonyms
- med26 Peptide, wu:fe06c07 Peptide, wu:fi75a09 Peptide, zgc:55993 Peptide, CRSP7 Peptide, CRSP70 Peptide, 5730493L18Rik Peptide, AI414941 Peptide, AW495270 Peptide, Crsp7 Peptide, Slc35e1 Peptide, crsp7 Peptide, mediator of RNA polymerase II transcription subunit 26 Peptide, cofactor required for Sp1 transcriptional activation, subunit 7 Peptide, mediator complex subunit 26 Peptide, mediator complex subunit 26 L homeolog Peptide, LOC725023 Peptide, crsp7 Peptide, MED26 Peptide, Med26 Peptide, med26.L Peptide
- Background
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. MED26 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-261 AC024075.4 20290-20550 c 262-726 AF104253.1 1-465 727-3184 AK128435.1 1414-3871
Alias Symbols: CRSP7, CRSP70
Protein Interaction Partner: CDK8,MED12,MED8,MED9,RBP1,CDK19,CDK8,CEBPB,MED1,MED10,MED11,MED12,MED13,MED13L,MED14,MED15,MED16,MED17,MED18,MED19,MED20,MED21,MED22,MED23,MED24,MED25,MED26,MED27,MED28,MED29,MED30,MED31,MED4,MED6,MED7,MED8,MED9,POLR2A,POLR2B,POLR2C,POLR2D,POLR2E,POLR2F,POLR2G,POLR2H,POLR2I,POLR2J,POLR2L
Protein Size: 600 - Molecular Weight
- 65 kDa
- Gene ID
- 9441
- NCBI Accession
- NM_004831, NP_004822
- UniProt
- O95402
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