Mediator Complex Subunit 7 (MED7) (Middle Region) Peptide
MED7
Reactivity: Human
Host: Synthetic
BP, WB, ChIP
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- Target See all MED7 products
- MED7 (Mediator Complex Subunit 7 (MED7))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- Sequence
- KRQRLETAER FQKHLERVIE MIQNCLASLP DDLPHSEAGM RVKTEPMDAD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MED7 Antibody(ARP57925_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MED7 (Mediator Complex Subunit 7 (MED7))
- Synonyms
- ARC34 Peptide, CRSP33 Peptide, CRSP9 Peptide, 1110063B05Rik Peptide, Crsp33 Peptide, Crsp9 Peptide, crsp9 Peptide, wu:fd99d12 Peptide, zgc:56241 Peptide, crsp9-A Peptide, med7-a Peptide, mediator complex subunit 7 Peptide, mediator complex subunit 7 L homeolog Peptide, mediator complex subunit Peptide, mediator complex subunit Med7 Peptide, MED7 Peptide, Med7 Peptide, med7 Peptide, med7.L Peptide
- Background
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CRSP33, CRSP9, MGC12284, ARC34
Protein Interaction Partner: HGS,MED8,MED9,BARHL1,CDK8,ESR1,ESR2,FXR2,HGS,HNF4A,MED1,MED10,MED19,MED22,MED26,MED28,MED29,MED9,UBAC1
Protein Size: 233 - Molecular Weight
- 27 kDa
- Gene ID
- 9443
- NCBI Accession
- NM_004270, NP_004261
- UniProt
- O43513
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