Nedd4 Family Interacting Protein 2 (NDFIP2) (Middle Region) Peptide
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- Target See all NDFIP2 products
- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SFCITNTIAG RYGAICGFGL SLIKWILIVR FSDYFTGYFN GQYWLWWIFL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NDFIP2 Antibody(ARP49441_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
- Synonyms
- MGC68708 Peptide, DKFZp459H0627 Peptide, N4WBP5A Peptide, 0710001O20Rik Peptide, 2810436B12Rik Peptide, 9130207N19Rik Peptide, N4wbp5a Peptide, mKIAA1165 Peptide, Nedd4 family interacting protein 2 S homeolog Peptide, Nedd4 family interacting protein 2 Peptide, ndfip2.S Peptide, NDFIP2 Peptide, ndfip2 Peptide, Ndfip2 Peptide
- Background
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NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.
Alias Symbols: FLJ25842, KIAA1165, N4wbp5a, N4WBP5A
Protein Interaction Partner: ITCH,NEDD4,NEDD4L,SMURF1,WWP2,NEDD4,SLC11A2
Protein Size: 336 - Molecular Weight
- 36 kDa
- Gene ID
- 54602
- NCBI Accession
- NM_019080, NP_061953
- UniProt
- Q9NV92
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