Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) Peptide
RIPK1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RIPK1 products
- RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RIPK1 antibody (Catalog #: AVARP02038_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
- Synonyms
- RIP Peptide, RIP1 Peptide, D330015H01Rik Peptide, Rinp Peptide, Rip1 Peptide, rip1 Peptide, ripk1 Peptide, xRIP1beta Peptide, xrip1 Peptide, receptor interacting serine/threonine kinase 1 Peptide, receptor (TNFRSF)-interacting serine-threonine kinase 1 Peptide, receptor interacting serine/threonine kinase 1 L homeolog Peptide, RIPK1 Peptide, Ripk1 Peptide, ripk1.L Peptide
- Background
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FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex.
Alias Symbols: RIP, RIP1
Protein Interaction Partner: EhV2gp75,HHV8gp76,MC159L,PTK2,TNFAIP3,TRAF2,TRAF2,ZFAND5,CASP8,CFLAR,CRADD,EGFR,FADD,FAS,HSP90AA1,IKBKG,MAP3K14,MAP3K3,MAP3K8,NFKB1,PTK2,RIPK1,RIPK3,RNF216,SQSTM1,TICAM1,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF1A,TRADD,TRAF1,TRAF2,TRAF3,TRAF5,TRIM38,TRPC4AP,ZFAND5,BIRC2,BIRC3,CA11,CASP10,CASP8,CFLAR,CRADD,CYLD,EGFR,FADD,FAS,HSP90AA1,IKBKG,ITCH,MAP3K14,MAP3K7,RIPK3,RNF11,RNF216,SQSTM1,TAB2,TAX1BP1,TICAM1,TNFAIP3,TNFRSF10B,TNFRSF1A,TRADD,TRAF1,TRAF2,TRAF3,TRAF5,TRPC4AP,UBC
Protein Size: 671 - Molecular Weight
- 76 kDa
- Gene ID
- 8737
- NCBI Accession
- NM_003804, NP_003795
- UniProt
- Q13546
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