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Relaxin 1 (RLN1) (Middle Region) Peptide

RLN1 Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN983014
  • Target See all Relaxin 1 (RLN1) products
    Relaxin 1 (RLN1)
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Western Blotting (WB), Blocking Peptide (BP)
    Sequence
    EIVPSFINKD TETIIIMLEF IANLPPELKA ALSERQPSLP ELQQYVPALK
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RLN1 Antibody(ARP56721_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Relaxin 1 (RLN1)
    Synonyms
    H1 Peptide, H1RLX Peptide, RLXH1 Peptide, bA12D24.3.1 Peptide, bA12D24.3.2 Peptide, Rln Peptide, rlx Peptide, RELAX Peptide, RLX1 Peptide, RNL1 Peptide, RLN1 Peptide, RLX Peptide, relaxin 1 Peptide, RLN1 Peptide, Rln1 Peptide
    Background
    Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds, however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.

    Alias Symbols: H1, RLXH1, bA12D24.3.1, bA12D24.3.2

    Protein Interaction Partner: RXFP1

    Protein Size: 185
    Molecular Weight
    21 kDa
    Gene ID
    6013
    NCBI Accession
    NM_006911, NP_008842
    UniProt
    P04808
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