Relaxin 1 (RLN1) (Middle Region) Peptide
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- Target See all Relaxin 1 (RLN1) products
- Relaxin 1 (RLN1)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP)
- Sequence
- EIVPSFINKD TETIIIMLEF IANLPPELKA ALSERQPSLP ELQQYVPALK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RLN1 Antibody(ARP56721_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Relaxin 1 (RLN1)
- Synonyms
- H1 Peptide, H1RLX Peptide, RLXH1 Peptide, bA12D24.3.1 Peptide, bA12D24.3.2 Peptide, Rln Peptide, rlx Peptide, RELAX Peptide, RLX1 Peptide, RNL1 Peptide, RLN1 Peptide, RLX Peptide, relaxin 1 Peptide, RLN1 Peptide, Rln1 Peptide
- Background
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Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds, however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.
Alias Symbols: H1, RLXH1, bA12D24.3.1, bA12D24.3.2
Protein Interaction Partner: RXFP1
Protein Size: 185 - Molecular Weight
- 21 kDa
- Gene ID
- 6013
- NCBI Accession
- NM_006911, NP_008842
- UniProt
- P04808
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