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Relaxin 2 (RLN2) (C-Term) Peptide

RLN2 Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN983015
  • Target See all Relaxin 2 (RLN2) products
    Relaxin 2 (RLN2)
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Western Blotting (WB), Blocking Peptide (BP)
    Sequence
    PQLQQHVPVL KDSSLLFEEF KKLIRNRQSE AADSSPSELK YLGLDTHSRK
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RLN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Relaxin 2 (RLN2)
    Synonyms
    H2 Peptide, H2-RLX Peptide, RLXH2 Peptide, bA12D24.1.1 Peptide, bA12D24.1.2 Peptide, RFLX Peptide, rln2 Peptide, rln3c Peptide, rlx3c Peptide, si:rp71-39b20.5 Peptide, relaxin 2 Peptide, insulin-like 3 (Leydig cell) Peptide, RLN2 Peptide, insl3 Peptide
    Background
    Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin.

    Alias Symbols: H2, RLXH2, bA12D24.1.1, bA12D24.1.2

    Protein Size: 185
    Molecular Weight
    21 kDa
    Gene ID
    6019
    NCBI Accession
    NM_134441, NP_604390
    UniProt
    P04090
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