Ribosomal Protein L32 (RPL32) (Middle Region) Peptide
RPL32
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all RPL32 products
- RPL32 (Ribosomal Protein L32 (RPL32))
- Protein Region
- Middle Region
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MEDTQDLNEQ SVKKTCPEAD VSEPQNSRSM EMQDLASPHA LVGGSDTPGS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Eya4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RPL32 (Ribosomal Protein L32 (RPL32))
- Synonyms
- L32 Peptide, AU020185 Peptide, rpL32-3A Peptide, zgc:136952 Peptide, 143250_at Peptide, BcDNA:RH03940 Peptide, CG7939 Peptide, Dmel\\CG7939 Peptide, M(3)99D Peptide, RP-49 Peptide, RP49 Peptide, RPL32 Peptide, Rp-49 Peptide, Rp49 Peptide, Rp49/RpL32 Peptide, Rpl32 Peptide, bs30a02.y1 Peptide, rp49 Peptide, rp49/RpL32 Peptide, ribosomal protein L32 Peptide, 50S ribosomal protein L32 Peptide, rpl32 Peptide, ribosomal protein L32 L homeolog Peptide, Ribosomal protein L32 Peptide, ribosomal protein L32 homolog32 Peptide, RPL32 Peptide, rpl32 Peptide, Rpl32 Peptide, rpl32.L Peptide, RpL32 Peptide
- Background
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Eya4 is a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Eya4 promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. It may be involved in development of the eye.
Alias Symbols: B130023L16Rik
Protein Interaction Partner: Eya4,Six1,Six2
Protein Size: 616 - Molecular Weight
- 67 kDa
- Gene ID
- 14051
- NCBI Accession
- NM_010167, NP_034297
- UniProt
- Q9Z191
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