SUMO1 Activating Enzyme Subunit 1 (SAE1) (N-Term) Peptide
SAE1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SAE1 products
- SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VTPEDPGAQF LIRTGSVGRN RAEASLERAQ NLNPMVDVKV DTEDIEKKPE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SAE1 Antibody(ARP52084_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))
- Synonyms
- AOS1 Peptide, HSPC140 Peptide, SUA1 Peptide, UBLE1A Peptide, 2400010M20Rik Peptide, 2610044L12Rik Peptide, AL033372 Peptide, AW743391 Peptide, D7Ertd177e Peptide, Sua1 Peptide, Uble1a Peptide, Aos1p Peptide, Sua1p Peptide, aos Peptide, sae2a Peptide, uble1a Peptide, wu:fa28b04 Peptide, zgc:86633 Peptide, SUMO1 activating enzyme subunit 1 Peptide, SUMO1 activating enzyme subunit 1 L homeolog Peptide, SAE1 Peptide, Sae1 Peptide, sae1.L Peptide, sae1 Peptide
- Background
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Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).
Alias Symbols: AOS1, FLJ3091, HSPC140, SUA1, UBLE1A
Protein Interaction Partner: UBA2,UBA2,SUMO2,SUMO3,UBA2,UBE2E3,CYP1B1,FKBP4,KIAA1409,RANBP2,Rangap1,SP100,SUMO1,SUMO2,SUMO3,UBA2,UBE2I
Protein Size: 346 - Molecular Weight
- 38 kDa
- Gene ID
- 10055
- NCBI Accession
- NM_005500, NP_005491
- UniProt
- Q9UBE0
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