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SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) (Middle Region) Peptide

SHC3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN983708
  • Target See all SHC3 products
    SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-SHC3 antibody (Catalog #: ARP56958_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))
    Synonyms
    N-Shc Peptide, NSHC Peptide, RAI Peptide, SHCC Peptide, ShcC Peptide, Rai Peptide, SHC adaptor protein 3 Peptide, src homology 2 domain-containing transforming protein C3 Peptide, SHC3 Peptide, Shc3 Peptide
    Background
    SHC3 is a signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. SHC3 is involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

    Alias Symbols: N-Shc, NSHC, SHCC, RAI

    Protein Interaction Partner: GRB2,ALK,APP,ARHGAP32,AXL,EGFR,FLT4,GRB2,NTRK1,NTRK2,RET,ALK,ARHGAP32,EGFR,NTRK1,NTRK2

    Protein Size: 594
    Molecular Weight
    64 kDa
    Gene ID
    53358
    NCBI Accession
    NM_016848, NP_058544
    UniProt
    Q92529
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