SMAD, Mothers Against DPP Homolog 5 (SMAD5) Peptide
SMAD5
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SMAD5 products
- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMAD5 antibody (Catalog #: ARP32006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
- Synonyms
- DWFC Peptide, JV5-1 Peptide, MADH5 Peptide, Madh5 Peptide, SBN Peptide, fb67b04 Peptide, mad Peptide, madh5 Peptide, sb:cb400 Peptide, smd5 Peptide, wu:fb67b04 Peptide, SMAD5 Peptide, DKFZp468M0619 Peptide, 1110051M15Rik Peptide, AI451355 Peptide, Dwf-C Peptide, MusMLP Peptide, SMAD family member 5 Peptide, SMAD5 Peptide, Smad5 Peptide, smad5 Peptide
- Background
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SMAD5 undergoes copy number gain and increased expression, rather than loss of expression, and therefore does not act as a tumor-suppressor gene in hepatocellular carcinoma. Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection.
Alias Symbols: DWFC, JV5-1, MADH5
Protein Interaction Partner: ACVR1,BCAT1,BMP6,CXXC5,FLNA,GDF6,HBG2,HOXA13,HOXD13,MBD1,MEN1,MTMR10,PNKP,PPIL4,PSMD11,PTPN12,RBM4,RYR2,SF3B1,SFPQ,SMAD1,SMAD4,SMURF2,SNRNP70,SNRPA,SOX5,SOX7,SUV39H1,SUV39H2,TOB1,U2AF2,VPS24,WWP1,ZEB2,ZNF8,ACVR1,PLEKHO1,RUNX1,RUNX2,RUNX3,SMAD4,SMURF1,TOB1,Zfp128
Protein Size: 465 - Molecular Weight
- 51 kDa
- Gene ID
- 4090
- NCBI Accession
- NM_005903, NP_005894
- UniProt
- Q99717
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