Structural Maintenance of Chromosomes 4 (SMC4) (Middle Region) Peptide
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- Target See all SMC4 products
- SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMC4 antibody (Catalog #: ARP46131_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))
- Synonyms
- CAP-C Peptide, CAPC Peptide, SMC-4 Peptide, SMC4L1 Peptide, hCAP-C Peptide, 2500002A22Rik Peptide, C79747 Peptide, Smc4l1 Peptide, cb788 Peptide, chunp6901 Peptide, fb99b10 Peptide, smc4l1 Peptide, wu:fb99b10 Peptide, xcap-c Peptide, ARABIDOPSIS THALIANA CHROMOSOME ASSOCIATED PROTEIN-C Peptide, ARABIDOPSIS THALIANA STRUCTURAL MAINTENANCE OF CHROMOSOME 4 Peptide, ATCAP-C Peptide, ATSMC3 Peptide, ATSMC4 Peptide, K15N18.7 Peptide, K15N18_7 Peptide, STRUCTURAL MAINTENANCE OF CHROMOSOMES 3 Peptide, structural maintenance of chromosome 3 Peptide, Structural maintenance of chromosomes protein 4 Peptide, structural maintenance of chromosomes 4 Peptide, structural maintenance of chromosomes 4 L homeolog Peptide, structural maintenance of chromosome 3 Peptide, smc-4 Peptide, SMC4 Peptide, Smc4 Peptide, smc4 Peptide, smc4.L Peptide, SMC3 Peptide
- Background
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SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Alias Symbols: CAPC, SMC4L1, hCAP-C, CAP-C, SMC-4
Protein Interaction Partner: NCAPD2,SMC2,DNMT3B,NCAPD2,SMC2
Protein Size: 1288 - Molecular Weight
- 147 kDa
- Gene ID
- 10051
- NCBI Accession
- NM_001002800, NP_001002800
- UniProt
- Q9NTJ3
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