Sp3 Transcription Factor (Sp3) (Middle Region) Peptide
Sp3
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all Sp3 products
- Sp3 (Sp3 Transcription Factor (Sp3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SP3 antibody (Catalog #: ARP33336_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Sp3 (Sp3 Transcription Factor (Sp3))
- Synonyms
- SPR2 Peptide, D130027J01Rik Peptide, SP3 Peptide, sp3 Peptide, zgc:162922 Peptide, Sp3 transcription factor Peptide, trans-acting transcription factor 3 Peptide, sp3a transcription factor Peptide, Sp3 transcription factor S homeolog Peptide, SP3 Peptide, Sp3 Peptide, sp3a Peptide, sp3.S Peptide
- Background
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SP3 is a transcriptional factor that can act as an activator or repressor, probably in a isoform-specific manner. SP3 binds to GT and GC boxes promoters elements.This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted.
Alias Symbols: DKFZp686O1631, SPR-2, SPR2
Protein Interaction Partner: SENP1,TNFSF10,E2F1,EP300,ESR1,GABPA,GRIN1,HDAC1,HDAC2,PIAS1,RB1,RBBP4,SP1,STK19,SUMO1,TP53,UBE2I,ZBTB7A,E2F1,GABPA,HDAC1,HDAC2,PIAS1,RBBP4,SFPQ,SP4,STK19
Protein Size: 781 - Molecular Weight
- 82 kDa
- Gene ID
- 6670
- NCBI Accession
- NM_003111, NP_003102
- UniProt
- Q02447
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