STAM Binding Protein (STAMBP) Peptide
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- Target See all STAMBP products
- STAMBP (STAM Binding Protein (STAMBP))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-STAMBP antibody (Catalog #: ARP53526_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- STAMBP (STAM Binding Protein (STAMBP))
- Synonyms
- AMSH Peptide, 5330424L14Rik Peptide, 5730422L11Rik Peptide, AW107289 Peptide, Amsh Peptide, mKIAA4198 Peptide, stambp Peptide, zgc:66147 Peptide, STAM binding protein Peptide, Stam binding protein Peptide, STAM binding protein a Peptide, STAMBP Peptide, Stambp Peptide, stambpa Peptide
- Background
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Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. STAMBP binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Alias Symbols: AMSH, MGC126516, MGC126518
Protein Interaction Partner: ALAS1,AMN,BMPR1B,CHMP1A,CHMP1B,CHMP4B,CTNNBL1,EPS15,GRAP2,GRB2,MAP2K5,RECQL5,RNF11,SMAD2,SMAD6,SMAD7,STAM,STAM2,UACA,VPS24,AFP,CHMP2A,CLINT1,CLTA,GRAP2,GRB2,OTUB1,PIK3C2A,RNF11,RNF11,SMAD6,SMAD7,SMURF2,STAM,STAM2,VPS24
Protein Size: 424 - Molecular Weight
- 48 kDa
- Gene ID
- 10617
- NCBI Accession
- NM_213622, NP_998787
- UniProt
- O95630
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