STIP1 Homology and U-Box Containing Protein 1 (STUB1) Peptide
STUB1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all STUB1 products
- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-STUB1 antibody (Catalog #: ARP43059_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
- Synonyms
- CHIP Peptide, HSPABP2 Peptide, NY-CO-7 Peptide, SDCCAG7 Peptide, UBOX1 Peptide, 0610033N24Rik Peptide, 2210017D18Rik Peptide, 2310040B03Rik Peptide, AW046544 Peptide, Chip Peptide, wu:fc22f04 Peptide, zgc:56076 Peptide, STUB1 Peptide, chip Peptide, ATCHIP Peptide, CARBOXYL TERMINUS OF HSC70-INTERACTING PROTEIN Peptide, carboxyl terminus of HSC70-interacting protein Peptide, STIP1 homology and U-box containing protein 1 Peptide, STIP1 homology and U-Box containing protein 1 Peptide, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase L homeolog Peptide, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase Peptide, STIP1 homology and U box-containing protein 1 Peptide, carboxyl terminus of HSC70-interacting protein Peptide, STUB1 Peptide, Stub1 Peptide, stub1 Peptide, stub1.L Peptide, LOC100282870 Peptide, CHIP Peptide
- Background
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STUB1 modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It has E3 ubiquitin-protein ligase activity and targets misfolded chaperone substrates towards proteasomal degradation. STUB1 mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.
Alias Symbols: CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1
Protein Interaction Partner: HSPA8,SMAD1,SMAD4,AR,ATCAY,BAG1,BMPR1B,DNAJB1,DYX1C1,ERBB2,ESR1,GPR37,HSF1,HSP90AA1,HSPA1A,HSPA1B,HSPA4,HSPA8,KHDRBS1,MAPT,MPP1,PSMA3,PSMD4,SMAD1,SMAD2,SMAD3,SMAD4,SMURF1,TGFBR1,UBB,UBE2D1,UBE2Q1,AHR,AKT1,BAG1,CYP3A4,DNAJB1,GPR37,GUCY1A2,HSP90AA1,HSPA1A,HSPA4,HSPA8,KHDRBS1,MAP3K5,MAPT,MCF2,MPP1,PARK2,RAF1,RUNX2,STUB1,TAL1,TP53,UBA1,UBE2D1,UBE2D2,UBE2E2,XIAP
Protein Size: 303 - Molecular Weight
- 35 kDa
- Gene ID
- 10273
- NCBI Accession
- NM_005861, NP_005852
- UniProt
- Q9UNE7
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