Syntaxin 1A (Brain) (STX1A) (N-Term) Peptide
STX1A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all STX1A products
- STX1A (Syntaxin 1A (Brain) (STX1A))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-STX1A antibody (Catalog #: AVARP13091_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- STX1A (Syntaxin 1A (Brain) (STX1A))
- Synonyms
- HPC-1 Peptide, P35-1 Peptide, STX1 Peptide, SYN1A Peptide, STX1A Peptide, hpc-1 Peptide, p35-1 Peptide, stx1 Peptide, sx1a Peptide, syntaxin1a Peptide, CG10716 Peptide, CG18615 Peptide, CG31136 Peptide, CG5448 Peptide, CT30033 Peptide, Dm Syx1 Peptide, DmSyx1A Peptide, Dmel\\CG31136 Peptide, SYX1A Peptide, Syt1A Peptide, Syx Peptide, Syx-1A Peptide, Syx1 Peptide, Syx1a Peptide, SyxA Peptide, anon-EST:Gibbs4 Peptide, anon-WO02059370.54 Peptide, dSyx1 Peptide, l(3)06737 Peptide, synt Peptide, syt-1A Peptide, syx Peptide, syx-1 Peptide, syx-1A Peptide, syx1 Peptide, syx1A Peptide, syntaxin 1A Peptide, syntaxin 1A (brain) Peptide, Syntaxin 1A Peptide, syntaxin-1A Peptide, STX1A Peptide, Stx1a Peptide, stx1a Peptide, Syx1A Peptide, EDI_005240 Peptide, Tsp_07354 Peptide
- Background
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Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor which produces explosive exocytosis. Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1253 BC064644.1 1-1253 1254-2117 BC000444.2 1209-2072
Alias Symbols: HPC-1, STX1, p35-1, P35-1, SYN1A
Protein Interaction Partner: CFTR,PSEN1,SLC6A3,VPS11,VPS18,ABCC9,APBA1,ATP4B,CACNA1D,CDK5,CFTR,CPLX1,CSNK2A1,CSNK2A2,DAPK1,FAM190B,KCNB1,NAPA,NSF,RAB27A,RIMS1,SCNN1A,SCNN1B,SCNN1G,SDCBP,SEPT2,SEPT5,SLC6A1,SLC6A2,SLC6A3,SLC6A4,SLC6A5,SLC6A9,SNAP23,SNAP25,SNAP29,SNPH,STX1A,STX8,STXBP1,STXBP2,STXBP5,STXBP6,SYT1,SYT4,SYT7,SYTL4,TRDMT1,TXLNA,TXLNB,UNC13B,VAMP1,VAMP2,VAMP7,VAMP8,VIM,VPS11,VPS18,ATP6V1B1,CDK5,CFTR,CPLX1,CPLX2,FAM190B,NAPA,RNF40,SCNN1A,SCNN1B,SCNN1G,SLC6A1,SLC6A4,SLC6A5,SLC6A9,SNAP23,SNAP25,SNAP29,STX1A,STXBP1,STXBP2,STXBP5,SYP,SYT1,SYTL4,Snap23,Snap25,TRDMT1,TXLNA,TXLNB,UNC13B,VAMP1,VAMP2,VAMP7,VAMP8,VAPB,VIM
Protein Size: 288 - Molecular Weight
- 33 kDa
- Gene ID
- 6804
- NCBI Accession
- NM_004603, NP_004594
- UniProt
- Q16623
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