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T-Box Brain Gene 1 (TBR1) (Middle Region) Peptide

TBR1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN984814
  • Target See all TBR1 products
    TBR1 (T-Box Brain Gene 1 (TBR1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TBR1 antibody (Catalog #: ARP31497_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TBR1 (T-Box Brain Gene 1 (TBR1))
    Synonyms
    TBR-1 Peptide, TES-56 Peptide, TBR1 Peptide, xtbr1 Peptide, tes-56 Peptide, MGC145853 Peptide, tbr1 Peptide, T-box, brain 1 Peptide, T-box, brain, 1 Peptide, T-brain homeobox protein Peptide, T-box brain gene 1 Peptide, T-box, brain, 1b Peptide, TBR1 Peptide, Tbr1 Peptide, tbr1 Peptide, tbr1b Peptide
    Background
    This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.

    Alias Symbols: MGC141978, TES-56, TBR-1

    Protein Interaction Partner: CASK,CASK,TSPYL2

    Protein Size: 682
    Molecular Weight
    74 kDa
    Gene ID
    10716
    NCBI Accession
    NM_006593, NP_006584
    UniProt
    Q16650
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