Topoisomerase (DNA) I (TOP1) (N-Term) Peptide
TOP1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Topoisomerase I (TOP1) products
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SNSEHKDSEK KHKEKEKTKH KDGSSEKHKD KHKDRDKEKR KEEKVRASGD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TOP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
- Synonyms
- CG6146 Peptide, Dmel\\CG6146 Peptide, TOP1 Peptide, TopI Peptide, Topo I Peptide, TopoI Peptide, dTopoI Peptide, l(1)G0134 Peptide, l(1)G0201 Peptide, l(1)G0229 Peptide, l(1)G0278 Peptide, l(1)top1 Peptide, top1 Peptide, topo I Peptide, topoI Peptide, DNA topoisomerase 1 beta Peptide, DNA topoisomerase I alpha Peptide, MGO1 Peptide, MGOUN 1 Peptide, MTE17.1 Peptide, MTE17_1 Peptide, TOP1BETA Peptide, TOPOISOMERASE 1 Peptide, TOPI Peptide, AI467334 Peptide, D130064I21Rik Peptide, Top-1 Peptide, Ab2-086 Peptide, topi Peptide, Topoisomerase 1 Peptide, DNA topoisomerase I Peptide, DNA topoisomerase I alpha Peptide, DNA topoisomerase 1 Peptide, topoisomerase (DNA) I Peptide, DNA topoisomerase I, gene 1 L homeolog Peptide, Top1 Peptide, top1 Peptide, topA Peptide, ZMO1193 Peptide, MRAD2831_RS63095 Peptide, Lferr_0016 Peptide, PC1_2015 Peptide, Za10_0136 Peptide, Gbro_0575 Peptide, Dd586_2108 Peptide, Kvar_3044 Peptide, Alvin_2069 Peptide, Dacet_0849 Peptide, Mrub_1615 Peptide, Arnit_2962 Peptide, Ndas_4953 Peptide, Trad_2377 Peptide, Acear_1653 Peptide, Mahau_0844 Peptide, Mesop_4109 Peptide, Thein_1586 Peptide, Theth_0241 Peptide, TOP1ALPHA Peptide, top-1 Peptide, TOP1 Peptide, top1.1.L Peptide
- Target Type
- Viral Protein
- Background
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This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Alias Symbols: TOPI
Protein Interaction Partner: NCL,PARP1,SFPQ,TOP1,BTBD1,BTBD2,CASP3,CASP6,CSNK2A1,FSHR,JUN,NCL,NCOA6,SFPQ,SRSF1,SRSF11,SUMO1,TDP1,TOP1,TOPORS,TP53,UBE2I,BTBD1,BTBD2,CDKN2A,CDT1,CSNK2A1,CSNK2A2,H2AFY,MGMT,NCL,PMS1,RRP1B,SFPQ,SRSF1,SRSF11,SUMO1,TAL1,TOPORS,TP53,UBE2I
Protein Size: 765 - Molecular Weight
- 91 kDa
- Gene ID
- 7150
- NCBI Accession
- NM_003286, NP_003277
- UniProt
- P11387
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