PHLDA3 Proteins

(Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))

p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor (By similarity).

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8 results

PHLDA3 Protein (AA 1-125) (His tag)

custom-made PHLDA3 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Phlda3 Protein, UniprotID Q9WV95

3 images

Catalog No. ABIN7556309

Details

PHLDA3 Protein (AA 1-127) (His tag)

custom-made PHLDA3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant PHLDA3 Protein, UniprotID Q9Y5J5

3 images

Catalog No. ABIN7550711

Details

PHLDA3 Protein (AA 31-127) (GST tag)

PHLDA3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (AA 31-127) protein (GST tag) (ABIN1314938)

1 image

Catalog No. ABIN1314938

Details

PHLDA3 Protein (AA 1-127) (GST tag)

PHLDA3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) (AA 1-127) protein (GST tag) (ABIN1314936)

1 image

Catalog No. ABIN1314936

Details

PHLDA3 Protein (AA 1-125) (Strep Tag)

custom-made PHLDA3 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3120128

Details

PHLDA3 Protein (AA 1-127) (Strep Tag)

custom-made PHLDA3 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3085960