PHLPP2 Proteins
(PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.
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7 results
custom-made
PHLPP2
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
PHLPP2
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
PHLPP2
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by SDS-PAGE
WB, ELISA
1 image
custom-made
PHLPP2
Origin: Mouse
Host: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, ELISA, SDS
custom-made
PHLPP2
Origin: Human
Host: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, ELISA, SDS
PHLPP2
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Rockland 009-001-s91s
PHLPP2
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
>95%
WB
Rockland Original
Aliases for PHLPP2 Proteins
PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) ProteinsPH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S) Proteins
PH domain and leucine rich repeat protein phosphatase 2 (phlpp2) Proteins
PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2) Proteins
AI481772 Proteins
C130044A18Rik Proteins
PHLPPL Proteins
phlppl Proteins
Phlppl Proteins
RGD1562857 Proteins
Did you look for something else?
- PHLDA3 Proteins
- PHLDA2 Proteins
- PHLDA1 Proteins
- PHKG2 Proteins
- PHKG1 Proteins
- PHKB Proteins
- PHKA2 Proteins
- PHKA1 Proteins
- PHIP Proteins
- PHGDH Proteins
- PHF8 Proteins
- PHF7 Proteins
- PHF6 Proteins
- PHF5A Proteins
- PHF23 Proteins
- PHF21A Proteins
- PHF2 Proteins
- PHF19 Proteins
- PHF17 Proteins
- PHF15 Proteins
- Phosducin Proteins
- Phosducin-Like Proteins
- Phosphatase and Actin Regulator 3 Proteins
- Phosphatase and Actin Regulator 4 Proteins
- Phosphate Cytidylyltransferase 1, Choline, alpha Proteins
- Phosphate Cytidylyltransferase 1, Choline, beta Proteins
- Phosphatidylinositol Binding clathrin Assembly Protein Proteins
- Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta Proteins
- PHOSPHO1 Proteins
- PHOSPHO2 Proteins
- phosphoenolpyruvate Carboxykinase 1 (Soluble) Proteins
- phosphofructokinase, Muscle Proteins
- Phosphoglucomutase 1 Proteins
- Phosphoglucomutase 2 Proteins
- Phosphoglucomutase 3 Proteins
- Phosphoglucomutase 5 Proteins
- phosphoglycerate Mutase 1 (Brain) Proteins
- Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Proteins
- Phospholamban Proteins
- Phospholipase B Proteins
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