anti-Human DEPTOR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended DEPTOR Antibody (supplied by: Log in to see )

Antigen
DEP Domain Containing MTOR-Interacting Protein (DEPTOR) Antibodies
  • DEP.6
  • DEPDC6
  • 4731402B04Rik
  • 9130412E02Rik
  • D15Ertd336e
  • D15Ertd597e
  • Depdc6
  • Depdc6-001
  • Depdc6-002
  • R75183
  • mKIAA4200
  • RGD1561030
  • RAPGEF4
  • DEP domain containing MTOR interacting protein
  • DEP domain containing MTOR-interacting protein
  • DEPTOR
  • Deptor
Epitope
AA 62-107
16
14
14
8
4
3
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
69
40
15
7
4
4
2
2
2
2
2
2
2
1
Host
Rabbit
60
8
1
Clonality
Polyclonal
Conjugate
This DEPTOR antibody is un-conjugated
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
52
22
21
15
15
14
12
1
Options
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Catalog No. ABIN1387597
$ 318.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1415968 IHC (p) WB HRP Rabbit IgG AA 62-107 Log in to see Polyclonal 0
1 ABIN2620009 ELISA IHC IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN1398097 IHC (p) WB Biotin Rabbit IgG AA 62-107 Log in to see Polyclonal 0
1 ABIN1733593 ICC IF IHC (p) WB Rabbit IgG Internal Region, AA 10-200 Log in to see Polyclonal 0
1 ABIN2962521 IHC (p) ELISA WB Rabbit Internal Region Log in to see Polyclonal 0

General

Antigen DEP Domain Containing MTOR-Interacting Protein (DEPTOR) Antibodies
Epitope AA 62-107
(16), (14), (14), (8), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(69), (40), (15), (7), (4), (4), (2), (2), (2), (2), (2), (2), (2), (1)
Host Rabbit
(60), (8), (1)
Clonality
Polyclonal
Conjugate This DEPTOR antibody is un-conjugated
(2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(52), (22), (21), (15), (15), (14), (12), (1)
Pubmed 1 reference available
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Product Details anti-DEPTOR Antibody

Target Details DEPTOR Application Details Handling References for anti-DEPTOR antibody (ABIN1387597) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human DEPTOR/DEPDC6
Isotype IgG
Plasmids, Primers & others

Target Details DEPTOR

Product Details anti-DEPTOR Antibody Application Details Handling References for anti-DEPTOR antibody (ABIN1387597) Images back to top
Antigen
Alternative Name Deptor (DEPTOR Antibody Abstract)
Background

DEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Synonyms: DEP.6, DEPDC6, DEP domain-containing mTOR-interacting protein, DEP domain-containing protein 6, DEPTOR

Gene ID 64798
UniProt Q8TB45
Pathways PI3K-Akt Signaling, RTK Signaling, Regulation of Cell Size

Application Details

Product Details anti-DEPTOR Antibody Target Details DEPTOR Handling References for anti-DEPTOR antibody (ABIN1387597) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-DEPTOR Antibody Target Details DEPTOR Application Details References for anti-DEPTOR antibody (ABIN1387597) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-DEPTOR antibody (ABIN1387597)

Product Details anti-DEPTOR Antibody Target Details DEPTOR Application Details Handling Images back to top
Product cited in:

Liu, Zhang, Liu, Li, Zhang, Li, Liu, Huang, Shen, Gu, Gao, Wu, Wu: "High DEPTOR expression correlates with poor prognosis in patients with esophageal squamous cell carcinoma." in: OncoTargets and therapy, Vol. 8, pp. 3449-55, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Images

Product Details anti-DEPTOR Antibody Target Details DEPTOR Application Details Handling References for anti-DEPTOR antibody (ABIN1387597) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-DEP Domain Containing MTOR-Interacting Protein (DEPTOR) (AA 62-107) antibody (ABIN1387597) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti DEPTOR/D...
Immunohistochemistry (IHC) image for anti-DEP Domain Containing MTOR-Interacting Protein (DEPTOR) (AA 62-107) antibody (ABIN1387597) Formalin-fixed and paraffin embedded rat liver labeled with Anti DEPTOR/DEPDC6 Polycl...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-DEP Domain Containing MTOR-Interacting Protein (DEPTOR) (AA 62-107) antibody (ABIN1387597) Paraformaldehyde-fixed, paraffin embedded rat brain, Antigen retrieval by boiling in ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-DEP Domain Containing MTOR-Interacting Protein (DEPTOR) (AA 62-107) antibody (ABIN1387597) Paraformaldehyde-fixed, paraffin embedded human colon cancer, Antigen retrieval by bo...