anti-Dog (Canine) MLST8 antibody for Immunohistochemistry

Recommended MLST8 Antibody (supplied by: Log in to see )

Antigen
MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) Antibodies
  • gbl
  • lts8
  • GBL
  • GbetaL
  • LST8
  • POP3
  • WAT1
  • 0610033N12Rik
  • AA409454
  • AI505104
  • AI851821
  • Gbl
  • fi37e04
  • wu:fi37e04
  • zgc:55455
  • zgc:85668
  • MTOR associated protein, LST8 homolog L homeolog
  • MTOR associated protein, LST8 homolog
  • MTOR associated protein, LST8 homolog (S. cerevisiae)
  • mlst8.L
  • MLST8
  • Mlst8
  • mlst8
Epitope
AA 150-200
23
10
10
9
8
7
6
5
4
3
3
2
2
2
2
1
1
Reactivity
Chicken, Chimpanzee, Cow (Bovine), Dog (Canine), Human, Macaque, Monkey, Mouse (Murine), Rat (Rattus)
125
65
48
9
8
7
4
4
4
3
3
3
3
2
2
2
2
1
1
1
Host
Rabbit
118
18
2
Clonality
Polyclonal
Conjugate
This MLST8 antibody is un-conjugated
8
8
7
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
117
47
36
17
13
8
7
3
2
2
2
2
Supplier
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Catalog No. ABIN2470104
$ 550.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN297122 IHC IHC (p) WB Rabbit AA 150-200 Log in to see Polyclonal 0

General

Antigen MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) Antibodies
Epitope AA 150-200
(23), (10), (10), (9), (8), (7), (6), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1)
Reactivity Chicken, Chimpanzee, Cow (Bovine), Dog (Canine), Human, Macaque, Monkey, Mouse (Murine), Rat (Rattus)
(125), (65), (48), (9), (8), (7), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Host Rabbit
(118), (18), (2)
Clonality
Polyclonal
Conjugate This MLST8 antibody is un-conjugated
(8), (8), (7), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(117), (47), (36), (17), (13), (8), (7), (3), (2), (2), (2), (2)
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Product Details anti-MLST8 Antibody

Target Details MLST8 Application Details Handling Images
Purification Protein G Column
Immunogen GBL antibody was raised against amino acids 150 - 200 of GBL (Human).
Plasmids, Primers & others

Target Details MLST8

Product Details anti-MLST8 Antibody Application Details Handling Images back to top
Antigen
Alternative Name GBL (MLST8 Antibody Abstract)
Background LST8, a 36-40 kDa intracellular protein, is a novel member of WD-40 protein family. It is a highly conserved cytosolic protein consisting of seven WD-40 repeating motifs. LST8 is a functional component of mTOR signaling complex (TORC1) and positively up-regulates the mTOR pathway. It interacts with the kinase domain of mTOR and stabilizes its interaction with raptor. LST8 participates in regulating cell growth and also in nutrient and growth factor-mediated mTOR signaling to S6K1. Reports suggest up-regulated expression of LST8 due to insulin indicating a possible role of LST8 in intracellular events related to insulin-receptor activation including insulin-stimulated glucose transport and glycogen synthesis. Northern Blot analysis detected a ubiquitous expression of LST8 with highest expression in brain and testis. Part of the mammalian target of rapamycin complex 1 (mTORC1), which is composed of mTOR, regulatory associated protein of mTOR (Raptor), mammalian LST8/G-protein beta-subunit like protein (mLST8/GbetaL) and the recently identified partner PRAS40. This complex is characterized by the classic features of mTOR by functioning as a nutrient/energy/redox sensor and controlling protein synthesis. The activity of this complex is stimulated by insulin, growth factors, serum, phosphatidic acid, amino acids (particularly leucine), and oxidative stress.
Gene ID 64223
UniProt Q9BVC4
Pathways PI3K-Akt Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Autophagy, CXCR4-mediated Signaling Events

Application Details

Product Details anti-MLST8 Antibody Target Details MLST8 Handling Images back to top
Application Notes GBL antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.
Restrictions For Research Use only

Handling

Product Details anti-MLST8 Antibody Target Details MLST8 Application Details Images back to top
Format Liquid
Buffer PBS, 0.2 % gelatin, 0.05 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies avoid freeze/thaw cycles.
Storage 4 °C/-20 °C
Storage Comment GBL antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Images

Product Details anti-MLST8 Antibody Target Details MLST8 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) (AA 150-200) antibody (ABIN2470104) anti-MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) (AA 150-200) antibody