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PPIB Products

(Cyclophilin B (PPIB))
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009].

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Featured PPIB Categories

PPIB Antibodies

High quality antibodies with extensive validation data.

PPIB ELISA Kits

Reliable ELISA kits for a wide range of species.

PPIB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPIB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (9)
Cat. No. ABIN7431392
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (6)
Cat. No. ABIN5519055
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN6243144
Quantity 200 μL
Datasheet Datasheet

Recommended PPIB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (5)
Cat. No. ABIN6730860
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966185
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966184
Quantity 96 tests
Datasheet Datasheet

Recommended PPIB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122545
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122544
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN666694
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PPIB products

Gegunde, Alfonso, Alvariño, Alonso, Botana: "Cyclophilins A, B, and C Role in Human T Lymphocytes Upon Inflammatory Conditions." in: Frontiers in immunology, Vol. 12, pp. 609196, (2021) (PubMed).

Choi, Suh, Rhee, Oh, Kim, Pak, Choe, Ha, Chon: "Exposure to tetrabromobisphenol A induces cellular dysfunction in osteoblastic MC3T3-E1 cells." in: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, Vol. 52, Issue 6, pp. 561-570, (2017) (PubMed).

Zhu, Wang, Zhao, Calimeri, Meng, Hideshima, Fulciniti, Kang, Ficarro, Tai, Hunter, McMilin, Tong, Mitsiades, Wu, Treon, Dorfman, Pinkus, Munshi, Tassone, Marto, Anderson, Carrasco: "The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells." in: Nature medicine, Vol. 21, Issue 6, pp. 572-80, (2015) (PubMed).

Pybus, Dean, West, Smith, Daramola, Field, Wilkinson, James: "Model-directed engineering of "difficult-to-express" monoclonal antibody production by Chinese hamster ovary cells." in: Biotechnology and bioengineering, Vol. 111, Issue 2, pp. 372-85, (2014) (PubMed).

Ray, Sullenger, White: "Further characterization of the target of a potential aptamer biomarker for pancreatic cancer: cyclophilin B and its posttranslational modifications." in: Nucleic acid therapeutics, Vol. 23, Issue 6, pp. 435-42, (2013) (PubMed).

Hayashi, Saito, Fujimura, Hara, Takamochi, Mitani, Mineki, Kazuno, Oh, Ueno, Suzuki, Yao: "Galectin-4, a novel predictor for lymph node metastasis in lung adenocarcinoma." in: PLoS ONE, Vol. 8, Issue 12, pp. e81883, (2013) (PubMed).

Ray, Rialon-Guevara, Veras, Sullenger, White: "Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker." in: The Journal of clinical investigation, Vol. 122, Issue 5, pp. 1734-41, (2012) (PubMed).

Barnes, Cabral, Weis, Makareeva, Mertz, Leikin, Eyre, Trujillo, Marini: "Absence of FKBP10 in recessive type XI osteogenesis imperfecta leads to diminished collagen cross-linking and reduced collagen deposition in extracellular matrix." in: Human mutation, Vol. 33, Issue 11, pp. 1589-98, (2012) (PubMed).

van Dijk, Nesbitt, Zwikstra, Nikkels, Piersma, Fratantoni, Jimenez, Huizer, Morsman, Cobben, van Roij, Elting, Verbeke, Wijnaendts, Shaw, Högler, McKeown, Sistermans, Dalton, Meijers-Heijboer, Pals: "PPIB mutations cause severe osteogenesis imperfecta." in: American journal of human genetics, Vol. 85, Issue 4, pp. 521-7, (2009) (PubMed).

Watashi, Ishii, Hijikata, Inoue, Murata, Miyanari, Shimotohno: "Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase." in: Molecular cell, Vol. 19, Issue 1, pp. 111-22, (2005) (PubMed).

Synonyms and alternative names related to PPIB

peptidylprolyl isomerase B (ppib), peptidylprolyl isomerase B (PPIB), peptidylprolyl isomerase B (Ppib), peptidylprolyl isomerase B (CC1G_03223), peptidylprolyl isomerase B (cyclophilin B) (Ppib), peptidylprolyl isomerase B L homeolog (ppib.L), peptidylprolyl isomerase B (cyclophilin B) (PPIB), peptidylprolyl isomerase B (cyclophilin B) (ppib), AA408962, AA553318, ACYPI004891, AI844835, cb87, Cphn-2, Cphn2, CyP-20b, cyp-s1, CYP-S1, cypb, CypB, CYPB, OI9, PPIB, Ppib, sb:cb87, scylp, Scylp, SCYLP, wu:fa97f08, zgc:73214, zgc:86796

Protein level used designations for PPIB

  • cyclophilin B
  • peptidylprolyl isomerase B
  • peptidylprolyl isomerase B (cyclophilin B)
  • PPIase B
  • peptidyl-prolyl cis-trans isomerase B
  • Peptidyl-prolyl cis-trans isomerase B
  • CYP-S1
  • S-cyclophilin
  • SCYLP
  • rotamase B
  • S-cyclophylin
  • cyclophilin-like protein
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