ADAM10 Protein (AA 214-672) (His tag)
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- Target See all ADAM10 Proteins
- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 214-672
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ADAM10 protein is labelled with His tag.
- Application
- Western Blotting (WB), ELISA
- Purpose
- ADAM 10
- Sequence
- TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI LARLKKAIFS PELYENIAE
- Characteristics
- recombinant ADAM 10 comprises a 459 amino acid fragment (214-672) corresponding to the ADAM 10 extracellular domain minus the signal peptide and prosequence and is expressed in E. coli with an aminoterminal hexahistidine tag.
- Purity
- > 95 %
- Top Product
- Discover our top product ADAM10 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 20 mM Tris-HCl pH 8.0, 5 mM EDTA, 50 % Glycerol
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C
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- Target
- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
- Alternative Name
- ADAM 10 (ADAM10 Products)
- Background
- ADAM 10 is a member of the ADAM family of membraneanchored cell surface proteins, which contain both a disintegrin and a metalloprotease domain. ADAM 10 is expressed in a wide variety of tissues and resides on both the cell surface and within the cytoplasm. ADAM10 has been implicated in proteolytic release of a number of cell surface proteins in particular TNF alpha,AD10, KUZ, EC 3.4.24.81, A desintegrin and metalloprotease domain 10, mammalian disintegrinmetalloprotease, Kuzbanian protein homolog, CDw156c antigen
- Molecular Weight
- 55.09 kDa
- UniProt
- O14672
- Pathways
- Notch Signaling, EGFR Signaling Pathway
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