CCL1 Protein (AA 24-96)

Catalog No. ABIN1096253

Product Details

Target: CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Protein Type: Recombinant

Protein Characteristics: AA 24-96

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human C-C Motif Chemokine 1/CCL1

Sequence: MKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK

Characteristics: Recombinant Human C-C Motif Chemokine 1/CCL1 is produced with our E. coli expression system. The target protein is expressed with sequence (K24-K96) of Human CCL1.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Alternative Name: ccl1 (CCL1 Products)

Synonyms: I-309 Protein, P500 Protein, SCYA1 Protein, SISe Protein, TCA3 Protein, BF534335 Protein, Scya1 Protein, Tca-3 Protein, CCLi6 Protein, chemokine Protein, C-C motif chemokine ligand 1 Protein, chemokine (C-C motif) ligand 1 Protein, CCL1 Protein, Ccl1 Protein

Background: Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection.
Alternative Names: C-C Motif Chemokine 1, Small-Inducible Cytokine A1, T Lymphocyte-Secreted Protein I-309, CCL1, SCYA1

Molecular Weight: 8.62 kDa

UniProt: P22362