Kallikrein 4 Protein (AA 27-254) (His tag)
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- Target See all Kallikrein 4 (KLK4) Proteins
- Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-254
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Kallikrein 4 protein is labelled with His tag.
- Purpose
- Recombinant Human Kallikrein 4/KLK4 (C-6His)
- Sequence
- SCSQIINGED CSPHSQPWQA ALVMENELFC SGVLVHPQWV LSAAHCFQNS YTIGLGLHSL EADQEPGSQM VEASLSVRHP EYNRPLLAND LMLIKLDESV SESDTIRSIS IASQCPTAGN SCLVSGWGLL ANGRMPTVLQ CVNVSVVSEE VCSKLYDPLY HPSMFCAGGG QDQKDSCNGD SGGPLICNGY LQGLVSFGKA PCGQVGVPGV YTNLCKFTEW IEKTVQASVD HHHHHH
- Characteristics
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Recombinant Human Kallikrein 4/KLK4 (C-6His)
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
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Kallikrein-Related Peptidase 4 (KLK4) (AA 1-254) protein (GST tag)
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Kallikrein-Related Peptidase 4 (KLK4) (AA 159-254) protein (GST tag)KLK4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Kallikrein-Related Peptidase 4 (KLK4) (AA 31-254) protein (His tag)Crystallography grade KLK4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Kallikrein-Related Peptidase 4 (KLK4) (AA 32-255) protein (His tag)Crystallography grade KLK4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Kallikrein-Related Peptidase 4 (KLK4) proteinKLK4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))
- Alternative Name
- kallikrein-4 (KLK4 Products)
- Synonyms
- ESMP1 Protein, KLK-L1 Protein, PSTS Protein, Prss17 Protein, AI2A1 Protein, ARM1 Protein, EMSP Protein, EMSP1 Protein, PRSS17 Protein, kallikrein Protein, Emsp1 Protein, kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) Protein, kallikrein related peptidase 4 Protein, kallikrein-related peptidase 4 Protein, Klk4 Protein, KLK4 Protein
- Background
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Recombinant Human Kallikrein 4 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (I31-S254) of Human KLK4 fused with a polyhistidine tag at the C-terminus.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. - Molecular Weight
- 25.44 kDa
- UniProt
- Q9Y5K2
- Pathways
- Complement System
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