LRRTM2 Protein (AA 34-422) (His tag)

Catalog No. ABIN1097107

Product Details

Target: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Protein Type: Recombinant

Protein Characteristics: AA 34-422

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This LRRTM2 protein is labelled with His tag.

Purpose: Recombinant Human Leucine-Rich Repeat-Containing Protein 2/LRRN2 (C-6His)

Sequence: CPPKCRCEKL LFYCDSQGFH SVPNATDKGS LGLSLRHNHI TELERDQFAS FSQLTWLHLD HNQISTVKED AFQGLYKLKE LILSSNKIFY LPNTTFTQLI NLQNLDLSFN QLSSLHPELF YGLRKLQTLH LRSNSLRTIP VRLFWDCRSL EFLDLSTNRL RSLARNGFAG LIKLRELHLE HNQLTKINFA HFLRLSSLHT LFLQWNKISN LTCGMEWTWG TLEKLDLTGN EIKAIDLTVF ETMPNLKILL MDNNKLNSLD SKILNSLRSL TTVGLSGNLW ECSARICALA SWLGSFQGRW EHSILCHSPD HTQGEDILDA VHGFQLCWNL STTVTVMATT YRDPTTEYTK RISSSSYHVG DKEIPTTAGI AVTTEEHFPE PDNAIFTQRV DHHHHHH

Characteristics: Recombinant Human Leucine-Rich Repeat Transmembrane Neuronal Protein 2/LRRTM2 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Cys34-Arg422) of Human LRRTM2 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Alternative Name: lrrtm2 (LRRTM2 Products)

Synonyms: sc:d0320 Protein, AI851755 Protein, BB129880 Protein, C630011A14Rik Protein, mKIAA0416 Protein, leucine rich repeat transmembrane neuronal 2 Protein, LRRTM2 Protein, lrrtm2 Protein, Lrrtm2 Protein

Sub Type: Fusionprotein

Background: Leucine-Rich Repeat Transmembrane Neuronal Protein 2 (LRRTM2) is a single-pass type I membrane protein that belongs to the LRRTM family. It contains ten LRR (leucine-rich) repeats, one LRRCT domain, and one LRRNT domain. LRRTM2 is expressed in neuronal tissues, and it interacts with DLG4 and NRXN1. LRRTM2 has been suggested to be involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. LRRTM2 also regulates the surface expression of AMPA receptors. LRRTM2 acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.
Alternative Names: Leucine-Rich Repeat Transmembrane Neuronal Protein 2, Leucine-Rich Repeat Neuronal 2 Protein, LRRTM2, KIAA0416, LRRN2

Molecular Weight: 45.55 kDa

UniProt: O43300

Pathways: Synaptic Membrane