PPIL1 Protein (AA 1-166) (His tag)

Catalog No. ABIN1097382

Product Details

Target: PPIL1 (Peptidylprolyl Isomerase (Cyclophilin)-Like 1 (PPIL1))

Protein Type: Recombinant

Protein Characteristics: AA 1-166

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PPIL1 protein is labelled with His tag.

Purpose: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase-Like 1/PPIase/PPIL1(N-6His)

Sequence: MGSSHHHHHH SSGLVPRGSH MAAIPPDSWQ PPNVYLETSM GIIVLELYWK HAPKTCKNFA ELARRGYYNG TKFHRIIKDF MIQGGDPTGT GRGGASIYGK QFEDELHPDL KFTGAGILAM ANAGPDTNGS QFFVTLAPTQ WLDGKHTIFG RVCQGIGMVN RVGMVETNSQ DRPVDDVKII KAYPSG

Characteristics: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase-Like 1/PPIase is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Gly166) of Human PPIL1 fused with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: PPIL1 (Peptidylprolyl Isomerase (Cyclophilin)-Like 1 (PPIL1))

Alternative Name: PPIL1 (PPIL1 Products)

Synonyms: CYPL1 Protein, PPIase Protein, hCyPX Protein, MGC79515 Protein, PPIL1 Protein, 1110060O10Rik Protein, AI327391 Protein, Cypl1 Protein, zgc:123245 Protein, peptidylprolyl isomerase like 1 Protein, peptidylprolyl isomerase like 1 L homeolog Protein, peptidyl-prolyl cis-trans isomerase-like 1 Protein, peptidylprolyl isomerase (cyclophilin)-like 1 Protein, PPIL1 Protein, ppil1.L Protein, ppil1 Protein, LOC707647 Protein, Ppil1 Protein

Sub Type: Fusionprotein

Background: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ,skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.
Alternative Names: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1, PPIase, Rotamase PPIL1, PPIL1, CYPL1

Molecular Weight: 20.4 kDa

UniProt: Q9Y3C6