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PGPEP1 Protein (His tag)

PGPEP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN1098474
  • Target See all PGPEP1 Proteins
    PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 15
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PGPEP1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product PGPEP1 Protein
  • Comment

    Synonyms: Pyroglutamyl-peptidase 1, Pyroglutamyl-peptidase I, Pcp, PGP, PGP-I, PGPI

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))
    Alternative Name
    PGPEP1 (PGPEP1 Products)
    Synonyms
    PGP Protein, PGP-I Protein, PGPI Protein, Pcp Protein, 2810003H13Rik Protein, Gm19458 Protein, PAP-I Protein, PAPI Protein, pyroglutamyl-peptidase I Protein, Pyroglutamyl-peptidase I Protein, Fnod_0998 Protein, Tlet_1256 Protein, Franean1_3440 Protein, Sked_37410 Protein, Arch_1014 Protein, Olsu_1567 Protein, Bcell_2984 Protein, Deima_2337 Protein, Spico_0458 Protein, Poras_1572 Protein, PGPEP1 Protein, Pgpep1 Protein
    Background
    PGPEP1 is an omega peptidase which removes pyroglutamyl residues from the amino termini of peptides and proteins. It is a cytosolic cysteine peptidase that is expressed in most cell types. The enzyme requires a thiolreducing agent for activity. PGPEP1 is potentially involved in the inactivation of biologically active peptides that possess an amino terminal pyroglutamyl group. Examples of such peptides include neurotensin, luteinizing hormone releasing hormone, and thyrotropinreleasing hormone. Recombinant human PGPEP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    25.5 kDa (232aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_060182
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