BPIFA1 Protein (His tag)
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- Target See all BPIFA1 Proteins
- BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BPIFA1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product BPIFA1 Protein
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- Comment
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Synonyms: BPI fold-containing family A, member 1, bA49G10.5, LPLUNC3, LUNX, NASG, PLUNC, SPURT
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by BCA assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 30% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))
- Alternative Name
- BPIFA1 (BPIFA1 Products)
- Synonyms
- LUNX Protein, NASG Protein, PLUNC Protein, SPLUNC1 Protein, SPURT Protein, bA49G10.5 Protein, Plunc Protein, BPI fold containing family A member 1 Protein, BPI fold containing family A, member 1 Protein, BPIFA1 Protein, Bpifa1 Protein
- Background
- BPIFA1, also known as PLUNC, belongs to the short subfamily of PLUNC family proteins and have homology only to the Nterminal domains of BPI. It is a secreted protein that is expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. BPIFA1 binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of BPIFA1 occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of BPIFA1 in the upper respiratory tract. Recombinant human BPIFA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 27.1 kDa (260aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_057667
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