NBL1 Protein (His tag)
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- Target See all NBL1 Proteins
- NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NBL1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NBL1 Protein
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- Comment
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Synonyms: Neuroblastoma suppressor of tumorigenicity 1, D1S1733E, DAN, DAND1, NB, NO3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))
- Alternative Name
- NBL1 (NBL1 Products)
- Synonyms
- D1S1733E Protein, DAN Protein, DAND1 Protein, NB Protein, NO3 Protein, D4H1S1733E Protein, Dana Protein, dand1 Protein, nbl1-a Protein, no3 Protein, 4.1N Protein, Epb41l1 Protein, NBL1 Protein, mKIAA0338 Protein, C1orf151-NBL1 Protein, dan Protein, zgc:77251 Protein, neuroblastoma 1, DAN family BMP antagonist Protein, neuroblastoma, suppression of tumorigenicity 1 Protein, neuroblastoma 1, DAN family BMP antagonist L homeolog Protein, neuroblastoma suppressor of tumorigenicity 1 Protein, erythrocyte membrane protein band 4.1 like 1 Protein, MINOS1-NBL1 readthrough Protein, NBL1 Protein, Nbl1 Protein, nbl1.L Protein, LOC535280 Protein, Epb41l1 Protein, MINOS1-NBL1 Protein, nbl1 Protein
- Background
- Neuroblastoma suppressor of tumorigenicity 1, also known as NBL1, is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. NBL1 is a candidate as a tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. It is produced in small neurons of the dorsal root ganglion and its expression is activated by MATH-1. Recombinant human NBL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 20 kDa (187aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_005371
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