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HOPX Protein (His tag)

HOPX Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098644
  • Target See all HOPX Proteins
    HOPX (HOP Homeobox (HOPX))
    Protein Type
    Recombinant
    Origin
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 4
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HOPX protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by using conventional chromatography.
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product HOPX Protein
  • Comment

    Synonyms: Homeodomain-only protein, CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    HOPX (HOP Homeobox (HOPX))
    Alternative Name
    HOPX (HOPX Products)
    Synonyms
    CAMEO Protein, HOD Protein, HOP Protein, LAGY Protein, NECC1 Protein, OB1 Protein, SMAP31 Protein, TOTO Protein, 1110018K11Rik Protein, 1200015P04Rik Protein, 2300002F06Rik Protein, AI848177 Protein, AW490897 Protein, Cameo Protein, Hdop Protein, Hod Protein, Hop Protein, Ob1 Protein, Obl Protein, Toto Protein, GIIg15b Protein, HOPX Protein, hod Protein, hop Protein, ob1 Protein, lagy Protein, toto Protein, cameo Protein, necc1 Protein, smap31 Protein, MGC147344 Protein, HOP homeobox Protein, HOPX Protein, Hopx Protein, hopx Protein
    Background
    HOPX, also known as homeodomain-only protein, acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. This protein prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Recombinant human HOPX protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
    Molecular Weight
    10.8 kDa (97aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_631957
    Pathways
    Regulation of Muscle Cell Differentiation
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