Ephrin B3 Protein (EFNB3) (AA 28-226) (His tag)

Catalog No. ABIN1098662

This Recombinant Ephrin B3 protein is produced in Escherichia coli (E. coli).

Quick Overview for Ephrin B3 Protein (EFNB3) (AA 28-226) (His tag) (ABIN1098662)

Target: Ephrin B3 (EFNB3)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 28-226

Purification tag / Conjugate: This Ephrin B3 protein is labelled with His tag.

Sequence: LSLEP VYWNSANKRF QAEGGYVLYP QIGDRLDLLC PRARPPGPHS SPNYEFYKLY LVGGAQGRRC EAPPAPNLLL TCDRPDLDLR FTIKFQEYSP NLWGHEFRSH HDYYIIATSD GTREGLESLQ GGVCLTRGMK VLLRVGQSPR GGAVPRKPVS EMPMERDRGA AHSLEPGKEN LPGDPTSNAT SRGAEGPLPP PSMP

Purification: > 90% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Synonyms: Ephrin-B3, EFL6, EPLG8, LERK8

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol, 0.1M NaCl, 2M urea

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: Ephrin B3 (EFNB3)

Alternative Name: Ephrin-B3

Background: EFNB3, also known as ephrin-B3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. Recombinant human EFNB3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Molecular Weight: 24.6 kDa (224aa)

NCBI Accession: NP_001397

Pathways: RTK Signaling