AICDA Protein (His tag)
-
- Target See all AICDA Proteins
- AICDA (Activation-Induced Cytidine Deaminase (AICDA))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AICDA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product AICDA Protein
-
Activation-Induced Cytidine Deaminase (AICDA) (AA 1-198) protein (GST tag)
AICDA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Activation-Induced Cytidine Deaminase (AICDA) (AA 1-198) protein (Strep Tag)Crystallography grade AICDA Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Activation-Induced Cytidine Deaminase (AICDA) (AA 1-198) protein (Strep Tag)Crystallography grade AICDA Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Activation-Induced Cytidine Deaminase (AICDA) (AA 26-312) protein (His tag)AICDA Origin: Saccharomyces cerevisiae Host: Yeast Recombinant > 90 % SDS
-
- Comment
-
Synonyms: Activation-induced cytidine deaminase, AID, ARP2, CDA2, HIGM2
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- AICDA (Activation-Induced Cytidine Deaminase (AICDA))
- Alternative Name
- AICDA (AICDA Products)
- Synonyms
- AID Protein, ARP2 Protein, CDA2 Protein, HIGM2 Protein, Aid Protein, Arp2 Protein, aid Protein, AICDA Protein, arp2 Protein, cda2 Protein, higm2 Protein, xlaid Protein, activation induced cytidine deaminase Protein, activation-induced cytidine deaminase Protein, activation-induced cytidine deaminase L homeolog Protein, AICDA Protein, Aicda Protein, aicda Protein, aicda.L Protein
- Background
- AICDA, also known as AID, is involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. This protein is required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. It may also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Recombinant human AICDA protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 26.1kDa (218aa)
- NCBI Accession
- NP_065712
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response
-
