c-MYC Protein (AA 330-439) (GST tag)

Catalog No. ABIN1311718

This Recombinant c-MYC protein is produced in Wheat germ. There is 1 publication available.

Quick Overview for c-MYC Protein (AA 330-439) (GST tag) (ABIN1311718)

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Protein Type: Recombinant

Origin: Human

Source: Wheat germ

Application: ELISA, Western Blotting (WB), Affinity Purification (AP), Antibody Array (AA)

Product Details

Protein Characteristics: AA 330-439

Purification tag / Conjugate: This c-MYC protein is labelled with GST tag.

Purpose: MYC (Human) Recombinant Protein (Q01)

Sequence: VRVLRQISNN RKCTSPRSSD TEENVKRRTH NVLERQRRNE LKRSFFALRD QIPELENNEK APKVVILKKA TAYILSVQAE EQKLISEEDL LRKRREQLKH KLEQLRNSCA

Characteristics: Human MYC partial ORF ( NP_002458, 330 a.a. - 439 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Seo, Kim, Bae, Soh, Lee: "Cdk5-mediated phosphorylation of c-Myc on Ser-62 is essential in transcriptional activation of cyclin B1 by cyclin G1." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15601-10, (2008) (PubMed).

Target Details

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name: MYC

Background: Full Gene Name: v-myc myelocytomatosis viral oncogene homolog (avian)
Synonyms: bHLHe39,c-Myc

Gene ID: 4609

NCBI Accession: NM_002467

Pathways: p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect