IGF-like family receptor 1 (IGFLR1) (AA 23-154) protein (Fc Tag)
-
- Target See all IGF-like family receptor 1 (IGFLR1) Proteins
- IGF-like family receptor 1 (IGFLR1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-154
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- Fc Tag
- Application
- SDS-PAGE (SDS)
- Specificity
- Binds to its ligand IGFL3 (human) in the subnanomolar range (< 1 ng /mL).
- Cross-Reactivity
- Human
- Characteristics
- Human IGFLR1 (aa 23-154) is fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.05EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IGFLR1 Protein
-
IGF-like family receptor 1 (IGFLR1) (AA 23-163) protein (His tag)
IGFLR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
IGF-like family receptor 1 (IGFLR1) (AA 185-345) protein (His tag)Crystallography grade IGFLR1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
IGF-like family receptor 1 (IGFLR1) (AA 185-355) protein (His tag)Crystallography grade IGFLR1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
IGF-like family receptor 1 (IGFLR1) (AA 23-163) protein (His tag)Crystallography grade IGFLR1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
IGF-like family receptor 1 (IGFLR1) (AA 21-163) protein (His tag)Crystallography grade IGFLR1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
IGF-like family receptor 1 (IGFLR1) (AA 23-355) protein (rho-1D4 tag)Crystallography grade IGFLR1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
IGF-like family receptor 1 (IGFLR1) (AA 21-345) protein (rho-1D4 tag)Crystallography grade IGFLR1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
-
- Target
- IGF-like family receptor 1 (IGFLR1)
- Alternative Name
- IGFLR1 (IGFLR1 Products)
- Background
- Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
- Molecular Weight
- ~50kDa (SDS-PAGE)
- UniProt
- Q9H665
-
