DLL1 Protein (AA 1-545) (DYKDDDDK Tag)
Quick Overview for DLL1 Protein (AA 1-545) (DYKDDDDK Tag) (ABIN1344209)
Target
See all DLL1 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-545
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Purification tag / Conjugate
- This DLL1 protein is labelled with DYKDDDDK Tag.
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Purpose
- DLL1 (human) (rec.)
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Cross-Reactivity
- Human
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Characteristics
- Signal peptide and extracellular domain of human DLL1 (aa 1-545) are fused at the C-terminus to a FLAG®-tag.
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Sterility
- Sterile filtered
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Endotoxin Level
- <0.1EU/μg purified protein (LAL test).
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Biological Activity Comment
- Inhibits adipogenesis of mesenchymal stem cells.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS.
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Handling Advice
- After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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Expiry Date
- 6 months
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- DLL1 (delta-Like 1 (DLL1))
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Alternative Name
- DLL1
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Background
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Delta-like Protein 1, Delta1
The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
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Molecular Weight
- ~70kDa (SDS-PAGE)
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UniProt
- O00548
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Pathways
- Notch Signaling, Stem Cell Maintenance
Target
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